Sugar acids and derivatives
Ambeed 2R 3R 4S 5S 6S 2Bromo6 methox
(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, 21085-72-3, 97%
Medchemexpress LLC D-Glucuronic acid | 6556-12-3 | 1 ML
D-Glucuronic acid is a crucial component of various anti-inflammatory proteoglycans, playing a role in embryonic development and inhibiting cell aggregation. This compound and its derivatives are known for their liver detoxifying properties and have demonstrated anti-tumor activity.
- Promotes early embryonic development
- Inhibits cell aggregation
- Functions as a liver detoxifier
- Derivatives possess anti-tumor activity
- Activates Toll-like receptor 4 (TLR4)
Medchemexpress LLC IL-18RAP Rhesus Mac 10ug | 10ug
IL-18 is a pleiotropic proinflammatory cytokine that is involved in induction of inflammatory mediators regulation of the cytotoxic activity of NK cells and T cells and differentiation and activation of both Th1 and Th2 cells IL-18 signals through its specific cell surface receptor IL-18R which comprises two subunits IL-18R and IL-18R beta IL-18 forms a signalling complex with the IL-18 receptor (R ) and (R ) chains at the plasma membrane which induces multiple inflammatory cytokines[2] IL-18R complex recruits the IL-1R- activating kinase and TNF- associated factor 6 which phosphorylates nuclear factor k - inducing kinase with subsequent activation of NF- k [3] IL-18R betaknockdown inhibits IL-18 driven tumor cell metastasis in C57/BL6 mice[4] IL-18RAP Protein Rhesus Macaque (HEK293 His) is a recombinant protein with a His label that consists of 357 amino acids (M1-R356) and is produced by HEK293 cells
Medchemexpress LLC 4-Methylumbelliferyl sulfate potassium | 15220-11-8 | 99.3% | 294.32 | 1 G
4-Methylumbelliferyl sulfate potassium is a fluorescent substrate commonly employed in biochemical and biomedical research to detect sulfatase activity. It comprises a sulfate group linked to a fluorescent molecule, which sulfatase enzymes can cleave. The cleavage of 4-Methylumbelliferyl sulfate releases a highly fluorescent product detectable via fluorescence microscopy or spectroscopy, enabling accurate detection and quantification of these enzymes in various biological samples.
- Fluorescent substrate
- Detects sulfatase activity
- Used in biochemical and biomedical research
- Enables accurate detection and quantification of enzymes
- Detectable via fluorescence microscopy or spectroscopy
Medchemexpress LLC [Ala11,D-Leu15]-Orexin B(human) | 532932-99-3 | 98.3% | 2857.26 | 10 MG
[Ala11,D-Leu15]-Orexin B(human) is a potent and selective orexin-2 receptor (OX2) agonist, demonstrating a 400-fold selectivity for OX2 (EC50=0.13 nM) over OX1 (52 nM).
- Potent and selective OX2 agonist
Medchemexpress LLC Glucuronic acid sodium | 7182-77-6 | 1 ML
Glucuronic acid sodium is a polysaccharide that exhibits anti-inflammatory activity.
- Assists in the healing of ulcerative colitis.
- Enhances the intestinal barrier by upregulating tight junction proteins like ZO-1 and Occludin.
- Modulates gut microbiota by increasing beneficial bacterial populations while suppressing harmful ones.
Medchemexpress LLC UDP-glucuronic acid (trisodium) | 63700-19-6 | 99.9% | 646.23 | 10 MG
UDP-glucuronic acid trisodium (Uridine-5'-diphosphoglucuronic acid trisodium salt) is a critical precursor for essential glycoconjugates across biological kingdoms, including mammalian glycosaminoglycans, plant cell wall polysaccharides, and bacterial capsule glycoglycerolipids. This product is a laboratory chemical intended for research use only by qualified scientists.
- Precursor for essential glycoconjugates in various biological organisms
- Promotes migration of liver cancer cells (Huh7, SK-Hep1, SNU449) by inducing the EMT process in vitro
- Decreases E-cadherin levels and increases vimentin levels in Huh7 and SNU449 cells in vitro
- Soluble in H2O (≥ 100 mg/mL) and DMSO (20 mg/mL with warming/ultrasonic)
- Recommended storage at -20°C, sealed, away from moisture
- In solvent, recommended storage at -80°C for 6 months or -20°C for 1 month
Medchemexpress LLC Plantainoside D | 147331-98-4 | 99.9% | 640.59 g/mol | C29H36O16 | 10 MG
Plantainoside D is a phenylethanoid glycoside research reagent reported to inhibit IKK-β and angiotensin-converting enzyme (ACE). It modulates voltage-dependent calcium channels and the PKC signaling cascade, reduces reactive oxygen species and NF-κB activation, and is used in studies of neuroprotection, anti-inflammation, antioxidant activity, and antihypertensive mechanisms.
- Phenylethanoid glycoside with IKK-β and ACE inhibitory activity.
- Modulates VDCCs and suppresses PKC signaling.
- Reduces ROS generation and inhibits NF-κB activation.
- High purity: 99.9%.
- CAS number 147331-98-4.
- Available as 10 MG solid and in DMSO solution formats for assays.
Medchemexpress LLC Sodium zirconium cyclosilicate | 17141-74-1 | 95.0% | 5 MG
Sodium zirconium cyclosilicate is an inorganic, microporous zirconium silicate used as a selective cation exchanger and potassium binder for laboratory research. Supplied as a white to off-white solid in small milligram quantities, it is intended for in vitro ion-exchange and potassium regulation studies.
- White to off-white solid form, insoluble and non-absorbed
- Highly selective potassium binding for ion-exchange research
- Available in small milligram quantities for laboratory use
- Store sealed at 4°C and protect from moisture
- Purity typically around 95.0% for research applications
Medchemexpress LLC Heparin sodium salt | 9041-08-1 | 15 kDa (for a specific form) | 25MG
Heparin sodium salt (Sodium heparin) is an anticoagulant that reversibly binds to antithrombin III (ATIII), significantly accelerating the rate at which ATIII inactivates coagulation enzymes thrombin factor IIa and factor Xa. It also notably inhibits exosome-cell interactions. Heparin is a complex linear polymer composed of chains of varying lengths and sequences.
- Acts as a potent anticoagulant.
- Enhances antithrombin-mediated inhibition of blood coagulation factors.
- Interacts with FGF-2 and FGFR-1, stabilizing FGF-FGFR binding.
- Promotes FGFR dimerization.
Alkali Scientific 4 Methylumbelliferyl α L Arabinopyranoside, 100 Milligrams
Methylumbelliferyl Arabinopyranoside is a high-purity reagent used in biochemical analysis, particularly in testing the activity of enzymes that hydrolyze arabinose-based substrates. This 100mg reagent is commonly employed in assays to study carbohydrate metabolism and glycosylation processes. It is ideal for use in enzyme-linked assays and metabolic studies focused on arabinose or other complex sugars. The high-quality purity of this reagent ensures consistent, reproducible results in laboratory experiments. Methylumbelliferyl Arabinopyranoside is a valuable tool in studying enzymes involved in plant cell wall degradation, microbial digestion, and carbohydrate enzymology.
Aobchem (3-Chloro-4-methoxyphenyl)(cyclopentyl)methanone | 95% | CAS 1094749-02-6 | C13H15ClO2 | 1g
(3-Chloro-4-methoxyphenyl)(cyclopentyl)methanone | 95% | CAS 1094749-02-6 | C13H15ClO2 | 1g